Table of Contents

HOW TO TREAT STEREOTYPIC MOVEMENT DISORDER 2025
GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF COMMON MENTAL DISORDERS
(Enacted under Decision No. 2058/QĐ-BYT dated May 14, 2020, by the Minister of Health)
Article 33
STEREOTYPIC MOVEMENT DISORDER
CHIEF EDITOR
Associate Professor, PhD Nguyễn Trường Sơn
CO-EDITOR
Associate Professor, PhD Lương Ngọc Khuê
PhD Nguyễn Doãn Phương
CONTRIBUTING AUTHORS
PhD Trần Thị Hà An
MSc Trịnh Thị Vân Anh
PhD Vũ Thy Cầm
MSc Trần Mạnh Cường
PhD Nguyễn Văn Dũng
PhD Vương Ánh Dương
PhD Lê Thị Thu Hà
MSc Trần Thị Thu Hà
MSc Phạm Công Huân
MSc Đoàn Thị Huệ
Specialist Doctor II Nguyễn Thị Minh Hương
MSc Vũ Thị Lan
- Nguyễn Phương Linh
Specialist Doctor II Nguyễn Thị Phương Loan
MSc Bùi Văn Lợi
MSc Nguyễn Thị Phương Mai
PhD Trần Nguyễn Ngọc
MSc Bùi Nguyễn Hồng Bảo Ngọc
MSc Trương Lê Vân Ngọc
MSc Bùi Văn San
PhD Dương Minh Tâm
MSc Phạm Xuân Thắng
MSc Lê Thị Phương Thảo
MSc Lê Công Thiện
MSc Vương Đình Thủy
Associate Professor, PhD Nguyễn Văn Tuấn
Specialist Doctor II Ngô Văn Tuất
MSc Đặng Thanh Tùng
MSc Vũ Sơn Tùng
MSc Cao Thị Ánh Tuyết
MSc Nguyễn Thị Ái Vân
Specialist Doctor II Hồ Thu Yến
MSc Nguyễn Hoàng Yến
CONTRIBUTORS TO EVALUATION AND FEEDBACK
Associate Professor, PhD Nguyễn Thanh Bình
PhD Vũ Thy Cầm
PhD Nguyễn Hữu Chiến
Specialist Doctor II Võ Thành Đông
PhD Lê Thị Thu Hà
Specialist Doctor II Đỗ Huy Hùng
PhD Nguyễn Mạnh Hùng
MSc Nguyễn Trọng Khoa
Specialist Doctor II Ngô Hùng Lâm
Associate Professor, PhD Phạm Văn Mạnh
Specialist Doctor II Trần Ngọc Nhân
PhD Dương Minh Tâm
MSc Đặng Duy Thanh
PhD Vương Văn Tịnh
Specialist Doctor II Lâm Tứ Trung
PhD Lại Đức Trường
PhD Cao Văn Tuân
Associate Professor, PhD Nguyễn Văn Tuấn
SECRETARIAT TEAM
MSc Đặng Thanh Tùng
MSc Trương Lê Vân Ngọc
BA Đỗ Thị Thư
Article 33
STEREOTYPIC MOVEMENT DISORDER
I. DEFINITION
Stereotypic movements are intentional, repetitive, often rhythmic actions commonly seen in typically developing children, with increased frequency in those diagnosed with pervasive developmental disorders or intellectual developmental disorders. Per ICD-10, stereotypic movement disorder involves voluntary, repetitive, nonfunctional, rhythmic movements not attributable to an underlying psychiatric or neurological condition.
II. ETIOLOGY
Causes can be viewed through behavioral, developmental, functional, and neurobiological lenses:
– Normal Development: Some stereotypic behaviors are typical in young children.
– Developmental Disorders: Progression from toddlerhood to later childhood may reflect conditions like intellectual disability or pervasive developmental disorders.
– Genetics: Lesch-Nyhan syndrome (X-linked recessive gene mutation) features intellectual disability, hyperuricemia, spasticity, and self-injurious stereotypies. Nail-biting shows familial patterns.
– Psychosocial Factors: Head-banging is linked to neglect or abandonment.
III. DIAGNOSIS
- Definitive Diagnosis
– Most prevalent in children with intellectual disability or pervasive developmental disorders.
– Harmless Stereotypies: Body rocking, head shaking, hair pulling/twisting, finger crossing, hand clapping.
– Nail-Biting: Begins as early as age 1, peaks by 12, affects all nails. Most cases are mild and don’t meet ICD-10 criteria. Associated with emotional states (anxiety, boredom); severe cases occur in profound intellectual disability or paranoid schizophrenia.
– Harmful Stereotypies: Repetitive head-banging, self-slapping, eye-poking, biting hands/lips/body parts. Severe cases may involve self-mutilation, posing life-threatening risks (e.g., secondary infections, sepsis).
– Head-Banging: Emerges at 6-12 months, male-to-female ratio 3:1. Rhythmic, persistent striking against cribs or hard surfaces; typically transient but may persist into mid-childhood.
– ICD-10 Criteria:
- Stereotypic movements causing bodily injury or disrupting normal activities.
- Duration ≥1 month.
- No other ICD-10 behavioral/psychiatric disorder (except intellectual disability) explains it.
– Subtypes:
– F98.40: No self-injury.
– F98.41: Self-injurious.
– F98.42: Mixed.
- Ancillary Testing
– No specific tests; diagnosis relies on clinical observation.
– Psychological Assessments: Beck/Hamilton depression scales, Zung/Hamilton anxiety scales, RADS (child depression), DASS (anxiety-depression-stress), DENVER II (development), CBCL (child behavior).
– Routine Tests: Complete blood count, biochemistry, urinalysis, ECG, abdominal ultrasound, chest X-ray.
- Differential Diagnosis
– Obsessive-Compulsive Disorder: Ritualistic, distress-driven behaviors.
– Tic Disorders: Involuntary, often distressing movements.
– Stereotyped Movement Disorder (Neurological): Linked to specific neurological conditions.
IV. TREATMENT
- Treatment Principles
– Combine behavioral interventions and pharmacotherapy.
– Address co-occurring conditions (e.g., anxiety, depression, autism).
– Prevent injury risks.
- Specific Treatments
Behavioral Therapy:
– Most effective, using rewards/punishments: Reduces symptoms in 90% of cases, with 40-70% achieving full remission.
– Techniques:
– Positive Reinforcement: Rewards appropriate behaviors.
– Functional Communication Training: Replaces inappropriate stereotypies with suitable verbal actions (e.g., saying “Sorry” instead of arm-flapping during conversation, redirecting focus).
– Habit Reversal: Substitutes unwanted repetitions with acceptable alternatives.
– Physical/Occupational Therapy: Enhances control and engagement.
Pharmacotherapy:
– Targets self-injurious behaviors:
– Antipsychotics (Older/Newer): Manage severe stereotypies.
– Antidepressants: Address co-occurring emotional issues.
– Valproic Acid: Used empirically, lacks robust clinical trial support.
– Naltrexone (Opiate Antagonist): May reduce self-injury.
– Supportive: Neuroprotectants (piracetam, ginkgo biloba, vinpocetine, choline alfoscerate, nicergoline), liver support, cognitive enhancers, nutrition (B vitamins, minerals, digestible diet, IV nutrition if needed).
Risk Prevention:
– Mitigate injury from severe stereotypies (e.g., head-banging, biting, eye-poking).
– Treat co-occurring psychiatric/physical conditions.
V. PROGNOSIS AND COMPLICATIONS
– Duration and course vary widely. ~80% of normal children exhibit purposeful, rhythmic, comforting movements that resolve by age 4.
– Severe stereotypies may range from brief stress-related episodes to persistent states. Severity depends on frequency, variety, and injury extent. Frequent, severe, self-injurious stereotypies have the poorest prognosis.
VI. PREVENTION
– No specific preventive measures exist.
– Early intervention is critical to prevent self-harm.
REFERENCES
Vietnamese
- Department of Psychiatry, Hanoi Medical University (2016), Lectures on Psychiatry. Medical Publishing House.
- Department of Psychiatry, Hanoi Medical University (2000), Organic Mental Disorders. Postgraduate Lecture Series.
- Department of Psychiatry & Medical Psychology, Military Medical Academy (2007), Psychiatry and Psychology. People’s Army Publishing House.
- Military Medical Academy (2016), Textbook of Psychiatric Disorders. People’s Army Publishing House, Hanoi.
- World Health Organization (1992), The International Classification of Diseases, 10th Revision (ICD-10): Mental and Behavioral Disorders. WHO, Geneva, 1992.
- World Health Organization (1992),ICD-10 Classification of Mental and Behavioral Disorders: Diagnostic Criteria for Research (translated by the Department of Psychiatry, Hanoi Medical University).
- David A., et al. (2010), Geriatric Psychiatry, Medical Publishing House, 2014. Translated by Nguyễn Kim Việt.
- Eduard V. (2009), Bipolar Disorder in Clinical Practice, Medical Publishing House, Hanoi.
- Kaplan & Sadock (2013), Pervasive Developmental Disorders, Synopsis of Child and Adolescent Psychiatry, Translated book, Medical Publishing House.
- Trần Hữu Bình (2016), Textbook of Psychiatric Disorders: Depressive Phase,Medical Publishing House, Hanoi.
- Lê Quang Cường (2005), Epilepsy, Medical Publishing House.
- Cao Tiến Đức (2017), Epilepsy: Mental Disorders in Epilepsy and Treatment, Medical Publishing House, pp. 9-15.
- Trần Viết Nghị (2000), Mental and Behavioral Disorders Due to Psychoactive Substance Use, Department of Psychiatry, Hanoi Medical University.
- Trần Viết Nghị, Nguyễn Minh Tuấn (1995), Treatment of Drug Addiction with Psychotropic Medications, Proceedings of the Scientific Conference on Drug Addiction Treatment Methods, Ministry of Health, Institute of Mental Health.
- Nguyễn Viết Thiêm (2000), Mental and Behavioral Disorders Due to Psychoactive Substance Use, Department of Psychiatry, Hanoi Medical University, pp. 103-111.
- Nguyễn Minh Tuấn (2016), Textbook of Psychiatric Disorders, Medical Publishing House.
- Nguyễn Minh Tuấn (2004), Heroin Addiction: Treatment Methods, Medical Publishing House.
- Nguyễn Minh Tuấn (2004), Diagnosis and Treatment of Dependence (Addiction), Medical Publishing House.
- Nguyễn Kim Việt (2016), Textbook of Psychiatric Disorders, Medical Publishing House, Hanoi.
- Nguyễn Kim Việt (2000), Mental and Behavioral Disorders Due to Psychoactive Substance Use,Department of Psychiatry, Hanoi Medical University.
- Nguyễn Kim Việt (2000), Organic Mental Disorders, Department of Psychiatry, Hanoi Medical University.
- Nguyễn Kim Việt, Nguyễn Văn Tuấn (2016), Textbook of Psychiatric Disorders, Department of Psychiatry, Hanoi Medical University, Medical Publishing House, pp. 74-79.
English
- The British Association for Psychopharmacology (2011). Evidence-based guidelines for the pharmacological treatment of schizophrenia: recommendations from the British Association for Psychopharmacology. J Psychopharmacol (Oxf), 25(5), 567–620.
- The National Institute for Health and Care Excellence (NICE) (2014). Psychosis and schizophrenia in adults: prevention and management. NICE guideline. CG178, 5-46.
- The National Institute for Health and Care Excellence (2014). Bipolar disorder: the assessment and management of bipolar disorder in adults,children and young people in primary and secondary care. September 2014.
- The National Institute for Health & Care Excellence – NICE (2010). The Treatmentand Management of Depression in Adults (updated edition). National Clinical Practice Guideline 90, 2010.
- NICE(2012), “Epilepsies: diagnosis and management ”, NICE
- Abdul S. K., Manjula M, Paulomi M. S., et al (2013), “Cognitive Behavior Therapy for Patients with Schizotypal Disorder in an Indian Setting: A Retrospective Review of Clinical Data”, the German Journal of Psychiatry, pp 1-7.
- Addington D., Abidi S., Garcia-Ortega I., et al. (2017). Canadian Guidelines for the Assessment and Diagnosis of Patients with Schizophrenia Spectrum and Other Psychotic Disorders. Can J Psychiatry, 62(9), 594–603.
- American Psychiatric Association (1994), “Amphetamine-type stimulants” Diagnostic and Statistical Manual of Mental Disorders”, Fourth Edition, DSM-Washington, DC
- American Psychiatric Association (2013). Alcohol-Related Disorders, Diagnostic and statistical manual of mental disorders DSM-5, American Psychiatric Publishing, 490-503.
- AmericanPsychiatric Association (2013). Opioid Diagnostic and statistical manual of mental disorders DSM-5, American Psychiatric.
- AmericanPsychiatric Association (2013). Diagnostic and statistical manual of mental disorders DSM-IV.
- Apurv K., Pinki D., Abdul K. (1997), “Treatment of acute and transient psychoticdisorders with low and high doses of oral haloperidol”, Indian Journal of Psychiatry, pp 2-8
- American psychiatric association (2010). Practice guideline for the Treatment of Patients With Schizophrenia, Second Edition. 184.
- Andreas M. (2012), “Schizoaffective Disorder”, Korean J Schizophr Res, pp 5-12.
- American Psychiatric Association (1994). The Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.
- Babalonis S, Haney M, Malcolm R.J, et al (2017). Oral cannabidiol does not produce a signal for abuse liability in frequent marijuana smokers. DrugAlcohol Depend. 172, 9-13.
- Benjamin J. S, Virginia A. S, Pedro R (2017). Substance-Related Disorders, Kapland & Sadock’s Comprehensive Textbook of Psychiatry, Lippincott Williams & Wilkins, Baltimore, Vol. 1.
- Benjamin J. S., Virginia A. S. (2007), “Substance-Related Disorders- Amphetamine (or Amphetamine-like) Behavioral Sciences/Clinical Psychiatry ”, Kaplan & Sadock’s Synopsis of Psychiatry 10th Edition, Lippincott Williams & Wilkins (2007)
- Bergamaschi M.M, Queiroz R.H.C, Zuardi A.W., et al (2011). Safety and side effects of cannabidiol, a Cannabis sativa constituent. Curr Drug Saf. 6(4), 237-249.
- Benzoni O., Fàzzari G., Marangoni C., Placentino A., Rossi A. (2015), “Treatment of resistant mood and schizoaffective disorders with electroconvulsive therapy: a case series of 264 patients”, Journal of Psychopathology, pp 266-268.
- Daniel R. R., Larry J. S., et al (2014), “Schizotypal personality disorders: a current review”, New York, pp 1-10.
- Dervaux A.M. (2010). Influence de la consommation de substances sur l’émergence et l’évolution des troubles psychotiques: le cas du cannabis. La these doctotraie, Universit ´e Pierre et Marie Curie – Paris VI, Paris, France.
- Dieter S., Steven C. S. (2014). “Drug treatment of epilepsy in adults ”, BMJ, p2-19.
- Early Psychosis Guidelines Writing Group (2010). Australian clinical guidelines for earlypsychosis 2nd Natl Cent Excell Youth Ment Health Melb, 2, 4–24.
- Elisa C., Amir H. C., Peter B. (2009), “Treatment of Schizoaffective Disorder”, Psychiatry (Edgemont),p 15-17.
- Felix-Martin W., Rafael C., (2016), “Current Treatment of Schizoaffective Disorder According to a Neural Network”, Neural Network. J Cytol Histol, pp 2-5
- Gary R., Donald A., Wiliam H., et al (2017), “Guideline for the pharmacotherapy of schizophrenia in adul”, The canadian journal of schiatry,pp 605-612.
- Galletly C., Castle D., Dark F., et al. (2016). Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for themanagement of schizophrenia and related disorders. Aust N Z J Psychiatry, 50(5), 410–472.
- Gautam S., Jain A., Gautam M., Vahia V. N., et al (2017). Clinical Practice Guidelines for the management of Depression. Indian J Psychiatry;59, Suppl
- Grunze H., et al. (2009). The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar
- Hasan A., Falkai P., Wobrock T., et al. (2012). World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia, Part 1: Update 2012 on the acute treatment of schizophrenia and the management of treatment resistance. World J Biol Psychiatry, 13(5), 318–
- Hasan A., Falkai P., Wobrock T., et al. (2013). World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Schizophrenia,Part 2: Update 2012 on the long-term treatment of schizophrenia and management of antipsychotic-induced side World J Biol Psychiatry, 14(1), 2–44.
- JakobsenD., Skyum E., Hashemi N., et al. (2017). Antipsychotic treatment of schizotypy and schizotypal personality disorder: a systematic review. J Psychopharmacol (Oxf), 31(4), 397–405.
- Jinsoo C., Theo C. M. (2017), “Current Treatments for Delusional Disorder”, Psychiatry, pp 5-20
- Jonathan K. B., Saeed F. (2012), “Acute and transient psychotic disorders: An overview of studies in Asia”, International Review of Psychiatry, pp 463-466
- Jochim, J., Rifkin-Zybutz, R., Geddes, J., et al (2019).Valproate for acute mania. Cochrane Database of Systematic Reviews.
- Kaplan& Sadock’s. Pocket Handbook of Psychiatric Drug Treatment
- Kennedy S. H., Lam R. W., McIntyre R. S., et al (2016). Canadian Network forMood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder. The Canadian Journal of Psychiatry, 61(9), 540–560.
- Krishna R.P., Jessica C., et al(2014), “Schizophrenia: overview and treatment options”, New York, pp 638-643.
- Lakshmi N. Y., Sidnay H. K., Saga V. P., et al (2018). Canadian network for mood and anxiety treatments (CANMAT) and international society for bipolar disorders (ISBD) 2018 guidelines for the management of patient with bipolar disorder. Bipolar disorders; 20:97-170
- Laskshmi N.Y., Sidney H. K. (2017). Kaplan and Sadock’s Comprehensive Textbook of Psychiatry: Pharmacological treatment of depression and bipolar disorders, Wolters Kluwer.
- Lakshmi N. Y., Sidney H. K., Saga V. P., et al (2018). Canadian network for mood and anxiety treatments (CANMAT) and international society for bipolar disorders (ISBD) 2018 guidelines for the management of patient with bipolar disorder. Bipolar disorders; 20:97-170
- Loya M., Dubey V., Diwan S., Singh H. (2017), “Acute and transient psychotic disorder and schizophrenia: On a continuum or distinct? A study of cognitive functions”, International Journal of Medicine Research, pp-4-7.
- Manschrec, Nealia L. K. (2006), “Recent Advances in the Treatment of Delusional Disorder”, The Canadian Journal of Psychiatry, pp-114-118
- Marcos E. M. B., Hermes M. T. B. (2016), “Schizoaffective Disorder and Depression. A case Study of a patient from ceará, Brazil”, iMedPub Journals, pp1-8
- Mesut Cetin (2015), “Treatment of Schizophrenia: Past, Present and Future”, Bulletin of Clinical Psychopharmacology, pp 96-98.
- Michael S., Christina Z., Gerd B., (2011), “Prevalence of delusional disorder among psychiatric inpatients: data from the German hospital register”, Neuropsychiatry, pp 319-322.
48. MIMS neurology & psychiatry disease management guidelines
- RajivTandon (2018), “Pharmacological Treatment of Schizophrenia 2017-2018 Update Summary”, org, pp 37-40.
- Robert E., et al (2014). Substance-Related and Addictive Disorders. The AmericainPsychiatric Publishing Textbook of Psychiatry, 6 th, DSM-5 Edition, Bristish Library, USA, 735 – 814.
- Rong C, Lee Y., Carmona N.E., et al (2017). Cannabidiol in medical marijuana: Research vistas and potential opportunities. Pharmacol Res. 121, 213-8.
- Skelton M., Khokhar W.A., Thacker S.P. (2015). Treatments for delusional disorder. Cochrane Database Syst Rev.
- Stahl S.M, Stein D.J, Lerer B (2012). Evidence based pharmacotherapy of illicit substance use disorders, Essential evidence based psychopharmacology
- Stephen M.S., Dan J.S., Bernard L. (2012). Evidence based pharmacotherapy of illicit substance use disorders, Essential evidence based
- Stahl S. (2009). Stahl’s essential psychopharmacology: neuroscientific basis and practical implications: Cambridge University Press.
- Stahl, M. (2013). Stahl’s essential psychopharmacology: neuroscientific basis and practical applications, Cambridge University Press.
- Vieta, Berk M., Schulze T. G., et al (2018). Bipolar disorders. Nature Reviews Disease Primers, 4, 18008
- Update2009 on the Treatment of Acute The World Journal of Biological Psychiatry. 10(2); 85-116.
If you need legal consulting, please Contact Us at NT International Law Firm (ntpartnerlawfirm.com)
You can also download the .docx version here.
“The article’s content refers to the regulations that were applicable at the time of its creation and is intended solely for reference purposes. To obtain accurate information, it is advisable to seek the guidance of a consulting lawyer.”

LEGAL CONSULTING SERVICES
090.252.4567NT INTERNATIONAL LAW FIRM
- Email: info@ntpartnerlawfirm.com – luatsu.toannguyen@gmail.com
- Phone: 090 252 4567
- Address: B23 Nam Long Residential Area, Phu Thuan Ward, District 7, Ho Chi Minh City, Vietnam